The State Key Lab of High Performance Ceramics and Superfine Microstructure
Shanghai Institute of Ceramics, Chinese Academy of Sciences
中国 科 学 院 上 海 硅 酸 盐 研 究 所 高 性 能 陶 瓷 和超 微 结 构 国 家 重 点 实 验 室
Organically-Capped Metal Nanoparticles for Soft Plasmonics, Soft Electronics and Targeted Theranostics
1Department of Chemical Engineering, Monash University, Melbourne VIC 3800, Australia
2Melbourne Centre for Nanofabrication, Melbourne VIC 3168, Australia
In this talk, I will briefly discuss our recent research activities in rational design and applications of organically-capped metal nanoparticles. Monodispersed metal nanoparticles are synthesized with controlled sizes and shapes, which are then modified by soft ligands including DNA, polymer and alkyl molecules. We have successfully applied such soft ‘meta-atoms’ to three major directions: (1) assembling soft plasmonic nanoparticle superlattice sheets (soft plasmene sheets); (2) fabricating soft elastic conductors (electronic skins) for wearable sensors; (3) DNA aptamer-targeted and light-controlled drug delivery.
Firstly, I will describe synthesis of soft ‘meta-atoms’ using nanospheres, nanorods, nanocages, nanocubes, and nanowires). Secondly, I will discuss how we manipulate the notoriously-difficult-to-manipulate ‘meta-atoms’ to form free-standing thinnest possible superlattice nanosheets, which could be used as a new-class SERS substrate which is soft, elastic and surface-attachable. This enabled the direct chemical identification on topologically complex surfaces such as banknotes and coins, and application as new-generation of anti-counterfeit security labels. Then I will discuss how we apply ultrathin gold nanowires to the design of electronic skin materials for wearable sensors enabling the monitoring of biological signals in real-time in-situ in a wireless fashion. Time permitting, I will also briefly mention our recent research on DNA aptamer-targetted plasmonic imaging and therapy.
Wenlong Cheng is a professor and director of research in the Department of Chemical Engineering at Monash University, Australia. He is also an Ambassador Tech Fellow in Melbourne Centre for Nanofabrication. He earned his PhD from Chinese Academy of Sciences in 2005 and his BS from Jilin University, China in 1999. He held positions in the Max Planck Institute of Microstructure Physics and the Department of Biological and Environmental Engineering of Cornell University before joining the Monash University in 2010. His research interest lies at the Nano-Bio Interface, particularly plasmonic nanomaterials, DNA nanotechnology, nanoparticle anticancer theranostics and electronic skins. He has published >90 papers including 3 in Nature Nanotech, 1 in Nature Mater and 1 in Nature Comm.